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CXCL14 Protéine

Cette protéine Recombinant CXCL14 est exprimée dans Escherichia coli (E. coli).
N° du produit ABIN1096464

Aperçu rapide pour CXCL14 Protéine (ABIN1096464)

Antigène

Voir toutes CXCL14 Protéines
CXCL14 (Chemokine (C-X-C Motif) Ligand 14 (CXCL14))

Type de proteíne

Recombinant

Activité biologique

Active

Origine

  • 9
  • 4
  • 4
Humain

Source

  • 16
  • 1
Escherichia coli (E. coli)

Application

Functional Studies (Func)

Pureté

> 95 % as determined by reducing SDS-PAGE.
  • Fonction

    Recombinant Human C-X-C Motif Chemokine 14/CXCL14

    Séquence

    SKCKCSRKGP KIRYSDVKKL EMKPKYPHCE EKMVIITTKS VSRYRGQEHC LHPKLQSTKR FIKWYNAWNE KRRVYEE

    Attributs du produit

    Recombinant Human C-X-C Motif Chemokine Ligand 14/CXCL14 produced in E. coli is a single non-glycosylated polypeptide chain containing 77 amino acids with a molecular mass of 9.4 kDa.

    Stérilité

    0.2 μm filtered

    niveau d'endotoxine

    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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  • Commentaires

    Biological activity: ED50 is 1.0-10.0 ng/ml as determined by the ability of Recombinant CXCL14 to induce calcium flux of prostaglandin E2 treated THP1 human acute monocytic leukemia cells.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 1M NaCl, pH 8.5.

    Conseil sur la manipulation

    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

    Stock

    4 °C/-20 °C/-80 °C

    Stockage commentaire

    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Date de péremption

    3 months
  • Antigène

    CXCL14 (Chemokine (C-X-C Motif) Ligand 14 (CXCL14))

    Autre désignation

    cxcl14

    Sujet

    Human Chemokine (C-X-C Motif) Ligand 14 (CXCL14) is constitutively expressed in certain normal tissues but is reduced or absent from many established tumor cell lines and human cancers. CXCL14 is known to be a chemoattractant for monocyte and dendritic cells. CXCL14 inhibits angiogenesis and exhibits antimicrobial activities. Mature human and mouse CXCL14 differ by only 2 amino acid residues.
    Alternative Names: C-X-C Motif Chemokine 14, Chemokine BRAKm MIP-2G, Small-Inducible Cytokine B14, CXCL14, MIP2G, NJAC, SCYB14

    Poids moléculaire

    9.4 kDa

    UniProt

    O95715

    Pathways

    Autophagy
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